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The observed failure of drugs targeting S-glutathionylation in clinical trials regarding ovarian cancer might be explained by resistance mechanisms such as increased/decreased rates of drug efflux/influx as cellular redox status affects transporters’ function or resistance to apoptosis through caspase-3 S-glutathionylation [73]

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Among others who might consider B12 injections are those who suffer from pernicious anemia, due to their difficulty maintaining proper red blood cell counts